Study: Can Prolonged Use of Ibuprofen Lead to Hearing Loss?

impaired-Horsel

Study: Can Prolonged Use of Ibuprofen Lead to Hearing Loss?

Is there a connection between the use of NSAIDS painkillers (eg Ibuprofen / Ibux) and hearing loss? A large study published in the American Journal of Epidemiology with 55850 female participants showed surprising results when it came to the question of whether there is a direct link between hearing loss and long-term use of such drugs - namely that those who take this type of drug regularly over a period of 6 years seems to have an increased chance of impaired hearing.

 

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It was scientists know Harvard Medical School which is behind the discovery. The researchers commented that due to increasing use of painkillers and other drugs, a thorough mapping of both short-term and long-term side effects is necessary. Similar studies have previously documented a link between the use of such drugs and impaired hearing among men - so this time they chose to focus on their female counterpart to see if the same factors were applicable there - they were. Do you have input? Use the comment field below or ours Facebook Page - the entire research study can be found at the link at the bottom of the article.

Brain

- 10 percent increased risk of impaired hearing / hearing loss

Prolonged use (ie 6 years or more) of Ibuprofen and acetaminophen (better known as paracetamol in Norway) led to a 10 percent increase in terms of risk of impaired hearing / hearing loss. The study shows a connection between the intake of NSAIDS and paracetamol in relation to hearing loss.

 

May affect quality of life

Hearing loss and impaired hearing can greatly affect the quality of life and daily functioning. It is important to identify which drugs can cause negative side effects and increase understanding of how such drugs affect our bodies.

Doctor talking to patient

Conclusion: Avoid prolonged use of Ibuprofen and Paracetamol

There are many who can not do without Ibux and Paracet in everyday life - unfortunately such long-term use can have negative side effects and it is known from the past that this can affect several parts of the health aspect. We would encourage those who are addicted to such medications in everyday life - perhaps due to chronic pain or the like - to contact their GP for a recommendation regarding physical treatment (eg with a physiotherapist, chiropractor or manual therapist). Because as we know, activity and movement are the best medicine - adapted to ability of course. You can of course contact us if you want a recommendation for clinics in your local area.

 

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Study: Duration of analgesic use and risk of hearing loss in women, Brian M. Lin et al., American Journal of Epidemiology, doi: 10.1093 / aje / kww154, published online December 14, 2016,

 

This is how caffeine can slow down Parkinson's disease

Coffee cup and coffee beans

This is how caffeine can slow down Parkinson's disease

Unfortunately, there is no cure for Parkinson's disease, but now researchers have come up with a newfound news in the form of a new study in which they have found that caffeine can prevent the buildup of a protein associated with the development of the disease. Previous studies have shown that coffee among other things can reduce liver damage. Another good reason to enjoy a good cup of freshly brewed coffee there.

 

Parkinson's disease is a progressive neurological condition that affects the central nervous system - and especially the motor aspect. Symptoms of Parkinson's may be tremor (especially in hands and fingers), difficulty moving and language problems. The exact cause of the condition is unknown, but new studies are constantly pointing out that a protein called alpha-synuclein plays an important role. This protein can deform and form protein clumps that we call Lewy bodies. These Lewy bodies accumulate in a special part of the brain called the substantia nigra - an area of ​​the brain that is primarily involved in the movement and formation of dopamine. This leads to a reduction in dopamine production, which leads to the characteristic movement problems seen in Parkinson's.

 

Now, researchers at the University of Saskatchewan College of Medicine have developed two caffeine-based components that they believe can stop alpha-synuclein from accumulating in this area.

coffee beans

Protection of dopamine producing cells

Previous research has been based and focused on protecting the cells that produce dopamine - but as the researchers in the new study said: "It only helps as long as there are actually cells left to defend." Therefore, they had a different approach, namely to prevent the accumulation of Lewy bodies from the beginning. With previous studies showing that caffeine – a central stimulant found in tea, coffee and cola – has a protective effect on dopamine cells, the researchers wanted to develop and identify specific components that could prevent such accumulation of the aforementioned proteins. They found that.

 

Drink coffee

Conclusion: Two specific caffeine components can provide a basis for treatment

The researchers identified two components called C8-6-I and C8-6-N that both exhibited the property they wanted – namely to bind to and prevent the protein alpha-synuclein, which is responsible for the accumulation of Lewy bodies, from deforming. The study therefore concludes that their findings can provide a basis for new treatment methods that can reduce and perhaps - potentially - stop the deterioration seen in Parkinson's disease. Very exciting and important research that can increase the quality of life for those affected - and their relatives.

 

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References

«Novel dimer compounds that bind α-synuclein can rescue cell growth in a yeast model overexpressing α-synuclein. a possible prevention strategy for Parkinson's disease, »Jeremy Lee et al., ACS Chemical Neuroscience, doi: 10.1021/acschemneuro.6b00209, published online 27 September 2016, abstract.