Autoimmune hepatitis

Autoimmune hepatitis is a chronic autoimmune disease affecting the liver. Autoimmune hepatitis occurs when the body's antibodies attack the liver cells and cause inflammation.

Symptoms of autoimmune hepatitis

The disease causes symptoms associated with liver problems, such as fatigue, muscle aches, fever, jaundice, abdominal pain - it can also lead to more serious symptoms such as scarring of the liver (cirrhosis).

If the condition is not treated, the symptoms will gradually worsen - and can lead to complete liver failure.

Clinical signs

As mentioned above under 'symptoms'.

Diagnosis and cause

The diagnosis is made through a series of clinical examinations (including blood tests), lab tests, urine analysis and thorough history. Particular attention is paid to certain antibodies in the blood test.
The condition requires liver biopsy to be completely safe.

Who is affected by the disease?

Autoimmune hepatitis affects 1-2 per 100000 / year. It affects women more often than men (7: 1) - like most other liver diseases.

Treatment

Medication treatment with corticosteroids and immunosuppressive drugs is the most common form of treatment. The treatment is successful in up to 60-80% of cases.

Liver transplant may be necessary if the condition has led to liver failure.

The most common form of treatment for autoimmune conditions is included immunosuppression - that is, drugs and measures that limit and cushion the body's own defense system. Gene therapy that limits inflammatory processes in immune cells has shown great progress in recent times, often in combination with increased activation of anti-inflammatory genes and processes.

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Also read: - Complete overview of autoimmune diseases

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